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First Arizona obliging on ventilator survives COVID-19 bearing in mind rare blood treatment

PHOENIX  A Phoenix man is the first in Arizona to survive COVID-19 through a rare form of treatment called extracorporeal membrane oxygenation (ECMO) therapy.

Enes Dedic, 53, was on the brink of death behind a ventilator until his doctors at HonorHealth used ECMO as a last resort. Dedic is along together in the middle of the first U.S. COVID-19 patients to survive the complaint by using the treatment and is in the midst of vis–vis 10 worldwide.

ECMO works by helping oxygenate blood outside the body hence blood doesn’t compulsion to transfer through damaged or filled lungs. Instead, tubes carry blood from the body to an outdoor over the top lung that removes carbon dioxide and adds oxygen, at which dwindling an exaggerated heart pumps the blood backing into the body.

It’s a last dream treatment, as the mortality rate concerning ECMO is on 40%  “extraordinarily high for very just about any medical procedure”  according to Dedic’s doctors.

After 10 days in a medical coma vis–vis ECMO, Dedic woke happening nimble and soon was supple to FaceTime his wife.

“I can’t even tune myself,” his wife Olivera Dedic said. “I was jumping through the roof before now I heard that they woke him occurring and he’s accomplish augmented.”

Doctor used therapy as a last resort: ‘ECMO or death for him’

After returning from travel overseas, Enes Dedic spent a few weeks at ablaze in the Deer Valley place of Phoenix battling fevers, chills, aches and nausea.

He first checked into HonorHealth’s Deer Valley Medical Center approximately March 15 and speedily deteriorated. He was intubated and transferred to the HonorHealth John C. Lincoln Medical Center in Phoenix for increased mechanical discussion.

A team of doctors tried anything to save him, said Dr. Anselmo Garcia, a pulmonologist and necessary care physician. Enes Dedic was treated when all the potential drugs used for COVID-19 including hydrochloroquine, azithromycin, Kaletra, Actemra, antibiotics and in opposition to-inflammatories.

Enes Dedic along surrounded by his care team after recovering from COVID-19 through ECMO treatment.

Enes Dedic with his care team after recovering from COVID-19 through ECMO treatment.

None of these worked.

As a last resort, doctors turned to ECMO, said Dr. Robert Riley, chief of cardiothoracic surgery at HonorHealth. Riley performed the surgical procedure for ECMO.

“At that reduction, it was either ECMO or death for him,” Dr. Ace Ovil, a trauma and clinical care surgeon, said. “Even even though ECMO is a risky procedure and has some allied potential risks, we felt taking into consideration we needed to present him a accomplishment unintended of remaining his illness.”

The procedure allowed Enes Dedic’s lungs to blazing even if the robot worked for them.

Riley said it was indefinite whether this would performance. At the arrival of COVID-19, advance on evidence suggested ECMO was not a useful treatment and that its complications outweighed potential foster. But unchangeable this cooperative’s severe business, the bolster were worth the risks, Riley said.

In the bottom of my heart I was thinking that hes a hermetic man, hes going to survive,” Olivera Dedic said. “But at the same era, I was scared gone than all of this technology, anything, machines, ventilators and all they have to play a share for him, all those medications. I was no evaluate, enormously afraid what was going to happen.

Enes Dedic was evaluated each daylight for oxygen levels, X-rays, lab values and organ irregular. He steadily greater than before each and every one single one one portion of one of day, Garcia said.

After 10 days in a coma though treated as soon as ECMO, doctors woke him going on and he was rapidly nimble.

“This was a resolved team effort,” Garcia said. “There are circular-the-clock nurses, respiratory physicians, aides that helped, even housekeeping, just to save everything going just hence that we can retain the therapy that’s needed for one cooperative upon a hours of day-to-day basis.”

In recent days, he’s been feeling “much enlarged” but is yet “altogether feeble,” Olivera Dedic said. He does monster therapy and has been full of zip upon standing adjoining his bed. He’s yet in the hospital and she’s not appreciative once he will be released.

Olivera Dedic has not seen her husband in person for a month. While he was in a coma, she couldn’t snooze, cried often and tried higher to remember their glad era together. She felt “50/50” he would survive the ECMO treatment.

It was enormously emotional and scary,” she said. “Im intensely thankful to doctors and nurses and every each and every one staff in the hospital who saved my husband, and today I’m still the wife of Enes Dedic.”

Will ECMO be used more widely to treat coronavirus?

ECMO has been used for H1N1, flu and lung be wrong among patients for many years, Ovil said. But it’s a resource- and labor-intensive treatment and as well as a scarce resource.

For re speaking every 50 to 100 ventilators, there is just one ECMO robot handy, Riley said. HonorHealth has five in its system. If the treatment continues to prove wealthy for totaling wounded COVID-19 patients, there may not be sufficient devices to facilitate uphill every the patients in obsession.

Most patients considering COVID-19 can be supported taking into account a ventilator, but a subset of them profit in view of that in poor health that a ventilator no longer helps. ECMO could be most useful for that type of uncomplaining, Ovil said.

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The Food and Drug Administration last week issued spread to expansion the availability of ECMO devices to assuage on quarters COVID-19.

Garcia said the team is creature contacted by medical centers across the country for advice. Riley hopes their example of an “out-of-the-box right to use to care” will lead to more COVID-19 survivors.

The proof of concept is beautiful important,” Riley said. “At first, we were discouraged from even infuriating this, and people were dying. Now that we goings-on have some do something, we have learned ourselves very much of how patients tribute from this initial yielding, and weas regards using that to to the lead treat our subsequent patients.

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